Is it useful to convert .nii.gz files to .nii - and what is the difference between the two formats?

Brenton Pyle DNAnexus Team

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    Ondrej Klempir DNAnexus Team

    Actually it could be useful - .gz means gzip, therefore gzip could produce a smaller file. Nifti is volume data, so it can take up a fair bit of permanent storage. Zipping it is purely for reducing the size of the file, and should not modify data. Some neuroinformatics tools directly support importing unzipped nii as well as zipped.

     

    Here is a nice tech discussion aroud nii vs niigz:

    https://lightrun.com/answers/ome-bioformats-nii-vs-niigz

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