What is the best way to extract a list of variants from WGS data?

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    Ondrej Klempir DNAnexus Team

    I think this would depend on your use case. You should be able to work with individual VCFs as well as with pVCF files. One of the suggestions would be to use Swiss Army Knife with vcftools and do some basic filtering / manipulations as it is shown for instance here:

     

    https://vcftools.github.io/man_latest.html

     

    Later, I would refine / postprocess the obtained data in Bash / Python and export it to a text file.

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