How to use Ensembl Variant Effect Predictor(VEP) on UKB data for GWAS?

I am currently trying to run a GWAS pipeline on UKB data. We have converted data to hail matrix table. However, I am facing challenges due to VEP docker image not being accessible in worker nodes.

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  • Comment author
    Ondrej Klempir DNAnexus Team

    Hi,

     

    In Spark based JupyterLab, specifying HAIL via "-ifeature" and "instance-count" might help to load the VEP docker image.

     

    dx run app-dxjupyterlab_spark_cluster -ifeature="HAIL-0.2.78-VEP-1.0.3" --instance-count=3 --instance-type mem1_ssd1_v2_x16

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